The effect of CYP2C9 gene polymorphisms on blood pressure lowering response to losartan in patients with essential hypertension

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Tanrikulu F. P., BABAOĞLU M. Ö., ÇAKIR B., BOZKURT A., Guven G. S.

CUKUROVA MEDICAL JOURNAL, cilt.47, sa.3, ss.1015-1023, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.17826/cumj.1093761
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1015-1023
  • Anahtar Kelimeler: Hypertension, losartan, CYP2C9, genetic polymorphism, pharmacogenetics, CLINICAL-RELEVANCE, VARIANTS, GENOTYPE
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Purpose: In this study, the possible effects of CYP2C9 polymorphisms on the clinical response to losartan were investigated in a group of hypertensive patients.