The effect of CYP2C9 gene polymorphisms on blood pressure lowering response to losartan in patients with essential hypertension

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Tanrikulu F. P., BABAOĞLU M. Ö., ÇAKIR B., BOZKURT A., Guven G. S.

CUKUROVA MEDICAL JOURNAL, vol.47, no.3, pp.1015-1023, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.17826/cumj.1093761
  • Journal Name: CUKUROVA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1015-1023
  • Keywords: Hypertension, losartan, CYP2C9, genetic polymorphism, pharmacogenetics, CLINICAL-RELEVANCE, VARIANTS, GENOTYPE
  • Hacettepe University Affiliated: Yes

Abstract

Purpose: In this study, the possible effects of CYP2C9 polymorphisms on the clinical response to losartan were investigated in a group of hypertensive patients.