Liver imaging findings of Wilson's disease

Akpinar E., Akhan O.

EUROPEAN JOURNAL OF RADIOLOGY, vol.61, no.1, pp.25-32, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 61 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1016/j.ejrad.2006.11.006
  • Journal Name: EUROPEAN JOURNAL OF RADIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.25-32
  • Hacettepe University Affiliated: Yes

Abstract

Wilson's disease is a rare, autosomal-recessive inherited disorder of copper metabolism resulting in accumulation of copper in liver. The form of liver disease varies, depending on the severity of the disease at the time of diagnosis and pathological findings include fatty changes, acute hepatitis, chronic active hepatitis, cirrhosis and occasionally fulminant hepatic necrosis. Liver imaging findings reflect a wide range of physiopathological processes of the disease and also demonstrate the associated findings of cirrhosis in cases with advanced disease. (C) 2006 Elsevier Ireland Ltd. All rights reserved.