6-(3,4-Difluorobenzoyl)-3-[2-(4-pyridyl)ethyl]-1,3-benzothiazol-2(3H)-one


Ozbey S. , GOKHAN N.

ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, vol.60, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60
  • Publication Date: 2004
  • Doi Number: 10.1107/s0108270104019730
  • Title of Journal : ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY

Abstract

A new type of benzothiazolinone derivative with potential pharmacological activity, viz. 6-(3,4-difluorobenzoyl)-3-[2-(4-pyridyl) ethyl]- 1,3-benzothiazol- 2(3H)-one, C21H14F2N2O2S, has been prepared and studied by NMR, IR and single-crystal X-ray diffraction techniques. The molecule is not planar, the pyridine and difluorobenzene moieties being located above and below the benzothiazole ring system. The carbonyl O atoms are involved in an intramolecular hydrogen-bond-type interaction.