3-Hydroxy-6-methyl-2-[4-(3-trifluoro-methylphenyl)piperazin-1-ylmethyl]-4H-pyran-4-one


KOYSAL Y., ISIK S., Aytemir M.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.60, 2004 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 60
  • Publication Date: 2004
  • Doi Number: 10.1107/s1600536803028642
  • Title of Journal : ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE

Abstract

In the structure of the title compound, 3-hydroxy-6-methyl-2-[4-(3-trifluoromethylphenyl)piperazin-1-ylmethyl]-4H-pyran- 4-one, C18H19F3N2O3, the piperazine ring displays an almost perfect chair conformation, with the substituents at the N atoms lying in equatorial positions. The conformation of the molecule is determined by intra- and intermolecular hydrogen bonds.