A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy

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Victor R. G., Sweeney H. L., Finkel R., McDonald C. M., Byrne B., Eagle M., ...Daha Fazla

NEUROLOGY, cilt.89, sa.17, ss.1811-1820, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 89 Sayı: 17
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1212/wnl.0000000000004570
  • Dergi Adı: NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1811-1820
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: To conduct a randomized trial to test the primary hypothesis that once-daily tadalafil, administered orally for 48 weeks, lessens the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD).