A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy


Victor R. G. , Sweeney H. L. , Finkel R., McDonald C. M. , Byrne B., Eagle M., ...Daha Fazla

NEUROLOGY, cilt.89, sa.17, ss.1811-1820, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 89 Konu: 17
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1212/wnl.0000000000004570
  • Dergi Adı: NEUROLOGY
  • Sayfa Sayıları: ss.1811-1820

Özet

Objective: To conduct a randomized trial to test the primary hypothesis that once-daily tadalafil, administered orally for 48 weeks, lessens the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD).