Nano-sized biopolymer levan: Its antimicrobial, anti-biofilm and anti-cancer effects

KOŞARSOY AĞÇELİ G., CİHANGİR N.

CARBOHYDRATE RESEARCH, vol.494, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 494
  • Publication Date: 2020
  • Doi Number: 10.1016/j.carres.2020.108068
  • Journal Name: CARBOHYDRATE RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Keywords: Levan, Nanobiopolymer, Pseudomonas mandelii, Antimicrobial, Antibiofilm, MFC-7, FERMENTATION, EXOPOLYSACCHARIDES, POLYSACCHARIDES, BIOSYNTHESIS, SUCROSE, ETHANOL, STRAIN, OPTIMIZATION, LEVANSUCRASE, BACTERIA
  • Hacettepe University Affiliated: Yes

Abstract

Among other polysaccharides, levan is a fructan with great potential in biotechnological applications due to its functional properties. The levan has only been available in small quantities because of its high cost. Here, a levan-producing microorganism was isolated from soil and identified as Pseudomonas mandelii. TGA, SEM, FTIR, H-1 NMR, C-13 NMR and Zetasizer analyses were used to characterize thermal properties and the morphology of the levan. It is the first time, the levan synthesized from P. mandelii is reported as nano sized.