Extranodal type T/NK-cell lymphoma with an atypical clinical presentation

AYDIN G. B., Akyuz C., Talim B., Evans S. E., Sahin S., Sari N., ...More

PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol.24, no.4, pp.291-299, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1080/08880010701441112
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.291-299
  • Hacettepe University Affiliated: Yes


Peripheral-type natural killer ( NK)- or T-cell lymphomas are rare disorders characterized with clonal proliferation of mature lymphocytes. They have been linked to chronic and active Epstein-Barr virus infection (CAEBV), which itself is not defined as a malignant hematological disorder. The authors present a patient with T/NK-cell lymphoma involving skin, kidneys, spleen, pancreas, and meninges. She was remarkable for having the mosaic feature of more than one type of extranodal T/NK-cell lymphoma. She also had mixed findings of CAEBV that might have been attributed both to hypersensitivity to mosquito bites and to hemophagocytic lymphohistiocytosis.