Dopamine-modified halloysite as new anticancer drug carrier system

Tansik E., KAPLAN CAN H.

POLIMERY, cilt.70, sa.5, ss.322-330, 2025 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 5
  • Basım Tarihi: 2025
  • Doi Numarası: 10.14314/polimery.2025.5.3
  • Dergi Adı: POLIMERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Central & Eastern European Academic Source (CEEAS), Compendex, Directory of Open Access Journals
  • Sayfa Sayıları: ss.322-330
  • Hacettepe Üniversitesi Adresli: Evet

Özet

A new anticancer drug carrier system based on polydopamine-functionalized halloysite (PDA-HNT) was developed. Hansen solubility parameters were used to select 5-fluorouracil (5-FU) as an anticancer drug. The obtained system was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), thermogravimetric analysis (TGA), and nuclear mag-netic resonance (1H NMR, 19F-NMR). It was shown that PDA-HNT may be a promising drug nanocarrier for delivery systems in cancer therapy.