Effects of clozapine and haloperidol treatment on plasma concentrations of androgen hormones and androgendependent organ changes in rats


Samadi A., Isikhan S., Ansari M. H. K. , Samadi M., SABUNCUOĞLU S.

INDIAN JOURNAL OF PHARMACOLOGY, vol.51, no.4, pp.269-275, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.4103/ijp.ijp_145_18
  • Journal Name: INDIAN JOURNAL OF PHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.269-275
  • Hacettepe University Affiliated: Yes

Abstract

OBJECTIVES: Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of haloperidol and clozapine on testosterone, cortisol, and corticosterone levels and also their influence on androgen-dependent organs in adult male Wistar rats.