Green Bioanalytical and Pharmaceutical Analysis of Voriconazole and Tadalafil by HPLC

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DOĞAN A., Basci N. E.

CURRENT PHARMACEUTICAL ANALYSIS, vol.13, no.6, pp.495-504, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 13 Issue: 6
• Publication Date: 2017
• Doi Number: 10.2174/1573412913666170210160251
• Journal Name: CURRENT PHARMACEUTICAL ANALYSIS
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.495-504
• Hacettepe University Affiliated: Yes

Abstract

Objective: Green pharmaceutical and bioanalytical methods for Voriconazole and Tadalafil were developed and validated using an environment friendly organic modifier without any extraction step. Replacing toxic solvent in bioanalytical HPLC is the first greening approach in chromatographic drug analysis in plasma.