Recent Developments in CE-MS Based Metabolomics


ÇELEBİER M., NENNİ M.

CURRENT ANALYTICAL CHEMISTRY, vol.17, no.9, pp.1229-1242, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 17 Issue: 9
  • Publication Date: 2021
  • Doi Number: 10.2174/1573411016999200709133339
  • Journal Name: CURRENT ANALYTICAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core
  • Page Numbers: pp.1229-1242
  • Keywords: Biomarkers, capillary electrophoresis-mass spectrometry, metabolome, metabolomics, review, XCMS, NUCLEAR-MAGNETIC-RESONANCE, ELECTROPHORESIS-MASS SPECTROMETRY, CAPILLARY-ELECTROPHORESIS, METABOLITE IDENTIFICATION, SAMPLE PREPARATION, HEPATOCELLULAR-CARCINOMA, BIOMARKER DISCOVERY, URINE METABOLOME, BLADDER-CANCER, VALIDATION
  • Hacettepe University Affiliated: Yes

Abstract

Background: Metabolomics has gained importance in clinical applications over the last decade. Metabolomics studies are significant because the systemic metabolome is directly affected by disease conditions. Metabolome-based biomarkers are actively being developed for early diagnosis and to indicate the stage of specific diseases. Additionally, understanding the effect of an intervention on a living organism at the molecular level is a crucial strategy for understanding novel or unexpected biological processes.