Recent Developments in CE-MS Based Metabolomics

ÇELEBİER M., NENNİ M.

CURRENT ANALYTICAL CHEMISTRY, cilt.17, sa.9, ss.1229-1242, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 17 Sayı: 9
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1573411016999200709133339
  • Dergi Adı: CURRENT ANALYTICAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core
  • Sayfa Sayıları: ss.1229-1242
  • Anahtar Kelimeler: Biomarkers, capillary electrophoresis-mass spectrometry, metabolome, metabolomics, review, XCMS, NUCLEAR-MAGNETIC-RESONANCE, ELECTROPHORESIS-MASS SPECTROMETRY, CAPILLARY-ELECTROPHORESIS, METABOLITE IDENTIFICATION, SAMPLE PREPARATION, HEPATOCELLULAR-CARCINOMA, BIOMARKER DISCOVERY, URINE METABOLOME, BLADDER-CANCER, VALIDATION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Metabolomics has gained importance in clinical applications over the last decade. Metabolomics studies are significant because the systemic metabolome is directly affected by disease conditions. Metabolome-based biomarkers are actively being developed for early diagnosis and to indicate the stage of specific diseases. Additionally, understanding the effect of an intervention on a living organism at the molecular level is a crucial strategy for understanding novel or unexpected biological processes.