A Challenging Diagnosis of Homozygous Prekallikrein Deficiency During the Preoperative Evaluation of an Infant With Intractable Seizures: A Literature Review of Surgical Management in This Disorder
LABMEDICINE, cilt.41, sa.5, ss.271-274, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 5
- Basım Tarihi: 2010
- Doi Numarası: 10.1309/lm5vs8fifrf1ohct
- Dergi Adı: LABMEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.271-274
- Hacettepe Üniversitesi Adresli: Evet
Özet
Prekallikrein is 1 of the factors involved in the contact phase of coagulation, and prekallikrein deficiency is characterized with no spontaneous or injury-related bleeding, despite markedly prolonged activated partial thromboplastin time (aPTT). The literature on the management of these patients during preoperative evaluation and delivery to surgery is limited, Herein we present a prekallikrein deficient 14-month-old boy who experienced no bleeding during or after epilepsy surgery with 1 course of fresh frozen plasma prior to surgery.