Capecitabine Induced Hand-Foot Syndrome: A Systematic Review of Case Reports


ARAS E., Tecen-Yucel K., Bayraktar-Ekincioglu A., Gullu I.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.9, sa.2, ss.178-191, 2019 (ESCI) identifier

Özet

Objective: Capecitabine, a prodrug of 5-fluorouracil, is currently used in the treatment of metastatic colorectal and breast cancers. The aim of this study was to review the pharmacological mechanisms, treatment strategies, and documented case reports of capecitabine-induced hand-foot syndrome (HFS).