HTK-Alcar, a Modified Organ Transplantation Solution, Decreases Ischemic Injury in the Rat Kidney Tissue

SARIBAŞ G. S., COŞKUN AKÇAY N., Akyol S. N., Dayanir D., Abraheem K., Bilge M., ...More

GAZI MEDICAL JOURNAL, vol.31, no.4, pp.622-629, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.12996/gmj.2020.143
  • Journal Name: GAZI MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Page Numbers: pp.622-629
  • Hacettepe University Affiliated: Yes

Abstract

Objectives: Histidine-tryptophan-ketoglutarate (HTK) solution is the storage solution used in organ transplantation. However, such solutions cannot completely eliminate tissue damage. Acetyl L-carnitine (Alcar) is a strong antioxidant. In this study we aimed to determine the protective effects of HTK solution prepared with Alcar in kidney tissue.