HTK-Alcar, a Modified Organ Transplantation Solution, Decreases Ischemic Injury in the Rat Kidney Tissue


SARIBAŞ G. S. , COŞKUN AKÇAY N., Akyol S. N. , Dayanir D., Abraheem K., Bilge M., ...More

GAZI MEDICAL JOURNAL, vol.31, no.4, pp.622-629, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.12996/gmj.2020.143
  • Journal Name: GAZI MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Page Numbers: pp.622-629
  • Hacettepe University Affiliated: Yes

Abstract

Objectives: Histidine-tryptophan-ketoglutarate (HTK) solution is the storage solution used in organ transplantation. However, such solutions cannot completely eliminate tissue damage. Acetyl L-carnitine (Alcar) is a strong antioxidant. In this study we aimed to determine the protective effects of HTK solution prepared with Alcar in kidney tissue.