Proton MR spectroscopy: Higher right anterior cingulate N-acetylaspartate/choline ratio in Asperger syndrome compared with healthy controls


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Oner O., Devrimci-Ozguven H., Oktem F., Yagmurlu B., Baskak B., Munir K. M.

AMERICAN JOURNAL OF NEURORADIOLOGY, cilt.28, sa.8, ss.1494-1498, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 8
  • Basım Tarihi: 2007
  • Doi Numarası: 10.3174/ajnr.a0625
  • Dergi Adı: AMERICAN JOURNAL OF NEURORADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1494-1498
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

BACKGROUND AND PURPOSE: One former study reported higher prefrontal N-acetylaspartate (NAA) levels in patients with Asperger syndrome (AS). The objective of the current study was to test the hypothesis that patients with AS would have higher dorsolateral prefrontal and anterior cingulate cortex NAA/creatine (Cr) and that NAA/Cr would be correlated with symptom severity.