Proton MR spectroscopy: Higher right anterior cingulate N-acetylaspartate/choline ratio in Asperger syndrome compared with healthy controls

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Oner O., Devrimci-Ozguven H., Oktem F., Yagmurlu B., Baskak B., Munir K. M.

AMERICAN JOURNAL OF NEURORADIOLOGY, vol.28, no.8, pp.1494-1498, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 8
  • Publication Date: 2007
  • Doi Number: 10.3174/ajnr.a0625
  • Journal Name: AMERICAN JOURNAL OF NEURORADIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1494-1498
  • Hacettepe University Affiliated: No

Abstract

BACKGROUND AND PURPOSE: One former study reported higher prefrontal N-acetylaspartate (NAA) levels in patients with Asperger syndrome (AS). The objective of the current study was to test the hypothesis that patients with AS would have higher dorsolateral prefrontal and anterior cingulate cortex NAA/creatine (Cr) and that NAA/Cr would be correlated with symptom severity.