Flavonoid, Phenylethanoid and Iridoid Glycosides from Globularia aphyllanthes


Kirmizibekmez H., BASSARELLO C., PIACENTE S., AKAYDIN G., Calis I.

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, vol.64, no.2, pp.252-256, 2009 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1515/znb-2009-0217
  • Journal Name: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.252-256

Abstract

A new flavone glycoside, 6-hydroxyluteolin 7-O-[6 '''-benzoyl-beta-D-glucopyranosyl-(1 -> 2)]-beta-D-glucopyranoside (aphyllanthoside, 1) was isolated from the MeOH extract of the aerial parts of Globularia aphyllanthes. Besides this new compound, two flavonoid glycosides (6-hydroxyluteolin 7-O-[6 '''-(E)-caffeoyl-beta-D-glucopyranosyl-(1 -> 2)]-beta-D-glucopyranoside and isoquercitrin), three phenylethanoid glycosides (verbascoside, rossicaside A, and trichosanthoside A), and 11 iridoid glycosides (aucubin, catalpol, 10-O-benzoylcatalpol, globularin, asperuloside, besperuloside, asperulosidic acid, daphylloside, scandoside, alpinoside and baldaccioside) were also obtained and characterized. Identification of the isolated Compounds was carried out by spectroscopic analysis including I D and 2D NMR experiments as well as HRMS.