The aim of this study was to determine whether social problem solving (SPS), interpersonal anger and guilt-shame variables predict university students' suicide probability, and their suicide probability based on their age and gender. For this purpose, data were collected from 381 female, 260 male students via Social Problem Solving Inventory, Suicide Probability, Interpersonal Anger and Guilt and Shame Scales. Suicide probability, negative self and exhaustion, dissociation from devotion to life and anger degrees of participants were predicted by SPS and interpersonal anger. Moreover, the best predictors of suicide probability and negative self and exhaustion were negative orientation to problem component of SPS and vengeful reactions component of interpersonal anger. Positive orientation to problem had the greatest effect on predicting dissociation from devotion to life, and impulsive/carelessness style had the highest effect on predicting anger. The best predictor of dissociation from devotion to life and anger was the vengeful reactions component of interpersonal anger. Suicide probability among participants did not differ between age and gender.