Is basal serum 17-OH progesterone a reliable parameter to predict nonclassical congenital adrenal hyperplasia in premature adrenarche?

GÖNÇ, ELMAS; ÖZÖN, ZEYNEP; ALİKAŞİFOĞLU, AYFER; ENGIZ, Ozlem; Bulum, BURCU; KANDEMİR, NURGÜN

Is basal serum 17-OH progesterone a reliable parameter to predict nonclassical congenital adrenal hyperplasia in premature adrenarche?

GÖNÇ E. N., ÖZÖN Z. A., ALİKAŞİFOĞLU A., ENGIZ O., Bulum B., KANDEMİR N.

TURKISH JOURNAL OF PEDIATRICS, cilt.53, sa.3, ss.274-280, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 53 Sayı: 3
Basım Tarihi: 2011
Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.274-280
Hacettepe Üniversitesi Adresli: Evet

Özet

To determine the critical features for the diagnosis of nonclassical 21 hydroxylase deficiency (NC21OHD) without performing adrenocorticotropic hormone (ACTH) test, we studied 186 cases with premature adrenarche. Clinical and laboratory features as well as basal 17-hydroxyprogesterone (17-OHP) were analyzed to determine factors important for differentiating NC21OHD.