Neuroprotective Effects of Quetiapine on Neuronal Apoptosis Following Experimental Transient Focal Cerebral Ischemia in Rats

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Yilmaz M. B., Tonge M., Emmez H., Kaymaz F., Kaymaz M.

JOURNAL OF KOREAN NEUROSURGICAL SOCIETY, vol.54, no.1, pp.1-7, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 54 Issue: 1
• Publication Date: 2013
• Doi Number: 10.3340/jkns.2013.54.1.1
• Journal Name: JOURNAL OF KOREAN NEUROSURGICAL SOCIETY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1-7
• Hacettepe University Affiliated: Yes

Abstract

Objective : This study was undertaken in the belief that the atypical antipsychotic drug quetiapine could prevent apoptosis in the penumbra region following ischemia, taking into account findings that show 5-hydroxytryptamine-2 receptor blockers can prevent apoptosis.