PLACENTA, vol.69, pp.64-70, 2018 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hydatidiform mole, Leukemia inhibitory factor (LIF), Insulin like growth factor-1 (IGF-1), Decidua, Trophoblast, Immunohistochemistry, HUMAN-PLACENTA, TROPHOBLAST INVASION, FACTOR LIF, FETOMATERNAL INTERFACE, CHORIOCARCINOMA CELLS, HUMAN ENDOMETRIUM, BINDING, IGF, RECEPTOR, BIOSYNTHESIS
Hacettepe University Affiliated:
Introduction: Leukemia inhibitory factor (LIF) and insulin like growth factor-1 (IGF-1) are two of the most important growth factors mediating trophoblast actions. We hypothesized that the localization and expression patterns of LIF and IGF-1 in partial and complete hydatidiform moles (HM) compared with normal first trimester placentas may provide an understanding of the proliferative processes in HMs.