The Effects of Desferroxamine on Bone and Bone Graft Healing in Critical-Size Bone Defects

Guzey S., Aykan A., Ozturk S., Avsever H., Karslioglu Y., Ertan A. A.

ANNALS OF PLASTIC SURGERY, cilt.77, sa.5, ss.560-568, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1097/sap.0000000000000679
  • Dergi Adı: ANNALS OF PLASTIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.560-568
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Autogenous bone grafts are still the criterion standard treatment option in critical-size bone defect reconstructions, and many therapies can affect its incorporation. In this study, it was aimed to research the effects of desferroxamine (DFO) application on bone and bone graft healing due to the effects of osteoblast and osteoclast regulation and stimulation of angiogenesis.