Cytomegalovirus infection in immunocompetent wheezy infants: the diagnostic value of CMV PCR in bronchoalveolar lavage fluid


Cinel G., Pekcan S., Ozcelik U., Alp A., Yalcin E., Ersoz D. D. , ...More

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.39, no.4, pp.399-403, 2014 (SCI-Expanded) identifier identifier identifier

Abstract

What is known and objective: Cytomegalovirus (CMV) pneumonitis in immunocompetent hosts is uncommon but is being recognized more frequently, particularly when presenting as severe viral pneumonia. The objective of this study was to examine lower respiratory tract CMV infection in immunocompetent wheezy infants, based on polymerase chain reaction (PCR) in bronchoalveolar lavage (BAL) fluid, to compare CMV PCR results in BAL and in blood samples and to evaluate the benefits of antiviral ganciclovir therapy in these patients.