Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury

Bolay, H; Gursoy-Ozdemir, Y; Sara, MEHMET; Onur, R; Can, A; Dalkara, TURGAY

doi:10.1161/01.str.0000013708.54623.de

Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury

Bolay H., Gursoy-Ozdemir Y., Sara Y., Onur R., Can A., Dalkara T.

STROKE, cilt.33, sa.5, ss.1369-1375, 2002 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 33 Sayı: 5
Basım Tarihi: 2002
Doi Numarası: 10.1161/01.str.0000013708.54623.de
Dergi Adı: STROKE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1369-1375
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Background and Purpose-Synaptic transmission is highly vulnerable to metabolic perturbations. However, the long-term consequences of transient metabolic perturbations on synapses are not clear. We studied the long-lasting changes in synaptic transmission and phosphorylation of presynaptic proteins in penumbral cortical neurons after transient moderate ischemia.