Ureterovesical junction obstruction causes increment in smooth muscle contractility, and cholinergic and adrenergic activity in distal ureter of rabbits


Yalcin S., Ertunc M., ARDIÇLI B., Kabakus I. M. , Tas T. S. , Sara Y., ...More

JOURNAL OF PEDIATRIC SURGERY, vol.48, no.9, pp.1954-1961, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 9
  • Publication Date: 2013
  • Doi Number: 10.1016/j.jpedsurg.2013.01.030
  • Journal Name: JOURNAL OF PEDIATRIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1954-1961
  • Keywords: Ureterovesical junction, Obstruction, Contractility, Distal ureter, UPPER URINARY-TRACT, CAJAL-LIKE CELLS, RENIN-ANGIOTENSIN SYSTEM, WHOLE-MOUNT PREPARATION, GENE-RELATED PEPTIDE, PRIMARY MEGAURETER, GUINEA-PIG, PYELOURETERAL MOTILITY, INTRAMURAL INNERVATION, ADRENOCEPTOR SUBTYPES
  • Hacettepe University Affiliated: Yes

Abstract

Background/Purpose: The controversy in management of primary obstructed megaureter necessitates further elucidation of the underlying pathophysiology. We evaluated smooth muscle contractility, and cholinergic, adrenergic and serotonergic activity of rabbit distal ureters after ureterovesical junction (UVJ) obstruction.