The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children

Keskin, Ozlem; Birben, ESRA; Sackesen, CANSIN; Soyer, Ozge; Alyamac, Evrim; Karaaslan, İBRAHİM; Tokol, Nihan; Ercan, Hulya; Kalayci, Omer

doi:10.1016/s1081-1206(10)60796-x

The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children

Keskin O., Birben E., Sackesen C., Soyer O. U., Alyamac E., Karaaslan C., ...Daha Fazla

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, cilt.97, sa.3, ss.321-328, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 97 Sayı: 3
Basım Tarihi: 2006
Doi Numarası: 10.1016/s1081-1206(10)60796-x
Dergi Adı: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.321-328
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: A C-T polymorphism at position 159 in the promoter of CD14 (C-159T) modulates the cellular response to endotoxin and significantly influences total IgE levels. The effect of this genetic variant on the cytokine response of the inflammatory cells is incompletely understood.