The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children

Keskin O., Birben E., Sackesen C., Soyer O. U., Alyamac E., Karaaslan C., ...Daha Fazla

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, cilt.97, sa.3, ss.321-328, 2006 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 97 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/s1081-1206(10)60796-x
  • Dergi Adı: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.321-328
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: A C-T polymorphism at position 159 in the promoter of CD14 (C-159T) modulates the cellular response to endotoxin and significantly influences total IgE levels. The effect of this genetic variant on the cytokine response of the inflammatory cells is incompletely understood.