The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children


Keskin O., Birben E. , Sackesen C. , Soyer O. U. , Alyamac E., Karaaslan C. , ...Daha Fazla

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, cilt.97, sa.3, ss.321-328, 2006 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 97 Konu: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/s1081-1206(10)60796-x
  • Dergi Adı: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
  • Sayfa Sayıları: ss.321-328

Özet

Background: A C-T polymorphism at position 159 in the promoter of CD14 (C-159T) modulates the cellular response to endotoxin and significantly influences total IgE levels. The effect of this genetic variant on the cytokine response of the inflammatory cells is incompletely understood.