Absence of Cytomegalovirus in Glioblastoma and Other High-grade Gliomas by Real-time PCR, Immunohistochemistry, and In Situ Hybridization

Holdhoff, Matthias; GÜNER, GÜNEŞ; Rodriguez, Fausto; Hicks, Jessica; Zheng, Qizhi; Forman, Michael; Ye, Xiaobu; Grossman, Stuart; Meeker, Alan; Heaphy, Christopher; Eberhart, Charles; De Marzo, Angelo; Arav-Boger, Ravit

doi:10.1158/1078-0432.ccr-16-1490

Absence of Cytomegalovirus in Glioblastoma and Other High-grade Gliomas by Real-time PCR, Immunohistochemistry, and In Situ Hybridization

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Holdhoff M., GÜNER G., Rodriguez F. J., Hicks J. L., Zheng Q., Forman M. S., ...More

CLINICAL CANCER RESEARCH, vol.23, no.12, pp.3150-3157, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 23 Issue: 12
Publication Date: 2017
Doi Number: 10.1158/1078-0432.ccr-16-1490
Journal Name: CLINICAL CANCER RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.3150-3157
Hacettepe University Affiliated: Yes

Abstract

Purpose: Reports of cytomegalovirus (CMV) detection in high-grade gliomas (HGG)/glioblastoma have been conflicting. We undertook a comprehensive approach to determine the presence or absence of CMV in tissue, plasma, and serum of HGG patients.