Effect of Topical Tetracycline on Seroma Formation in the Lichtenstein Technique: A Prospective Randomized Study
INTERNATIONAL SURGERY, vol.99, no.2, pp.147-152, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 99 Issue: 2
- Publication Date: 2014
- Doi Number: 10.9738/intsurg-d-13-00199.1
- Journal Name: INTERNATIONAL SURGERY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.147-152
- Keywords: Lichtenstein technique, Polypropylene mesh, Topical tetracycline, Seroma, Ultrasonography, INGUINAL-HERNIA REPAIR, SCLEROTHERAPY, HYDROCHLORIDE, HERNIOPLASTY, MANAGEMENT, EFFUSION
- Open Archive Collection: AVESIS Open Access Collection
- Hacettepe University Affiliated: Yes
Abstract
We sought to investigate whether application of topical tetracycline has a limiting effect on seroma formation in patients undergoing hernia repair using a polypropylene mesh. This study was conducted in 96 patients undergoing an elective groin hernia repair. Patients were randomized and divided into 2 groups. After the graft was placed, and before external oblique muscle aponeurosis was closed, 5 mL tetracycline was administered on the graft in the tetracycline group (tetra group, n = 50), and 5 mL isotonic saline was administered in the control group (n = 46) without putting in a drain. Seroma checks via surface ultrasonography were done. Seroma amounts measured on the first day were significantly higher in the tetra group (P = 0.04). There were no significant differences regarding seroma measurements on the seventh day or in the first and second months. Topical tetracycline application has no limiting effect on seroma formation after a groin hernia operation.