Effect of Topical Tetracycline on Seroma Formation in the Lichtenstein Technique: A Prospective Randomized Study

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Turk E., Karagulle E., ÇOBAN ÇİFÇİ G., Yildirim E., Moray G.

INTERNATIONAL SURGERY, vol.99, no.2, pp.147-152, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 99 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.9738/intsurg-d-13-00199.1
  • Journal Name: INTERNATIONAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.147-152
  • Keywords: Lichtenstein technique, Polypropylene mesh, Topical tetracycline, Seroma, Ultrasonography, INGUINAL-HERNIA REPAIR, SCLEROTHERAPY, HYDROCHLORIDE, HERNIOPLASTY, MANAGEMENT, EFFUSION
  • Open Archive Collection: AVESIS Open Access Collection
  • Hacettepe University Affiliated: Yes

Abstract

We sought to investigate whether application of topical tetracycline has a limiting effect on seroma formation in patients undergoing hernia repair using a polypropylene mesh. This study was conducted in 96 patients undergoing an elective groin hernia repair. Patients were randomized and divided into 2 groups. After the graft was placed, and before external oblique muscle aponeurosis was closed, 5 mL tetracycline was administered on the graft in the tetracycline group (tetra group, n = 50), and 5 mL isotonic saline was administered in the control group (n = 46) without putting in a drain. Seroma checks via surface ultrasonography were done. Seroma amounts measured on the first day were significantly higher in the tetra group (P = 0.04). There were no significant differences regarding seroma measurements on the seventh day or in the first and second months. Topical tetracycline application has no limiting effect on seroma formation after a groin hernia operation.