P16 and p27 tumor suppressor gene methylation status in childhood Wilms tumor cases


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Bozkurt C., BOZKURT S., Arda N., Ertem A. U., Sahin G., Yuksek N., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.41, no.4, pp.633-638, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.3906/sag-0909-296
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.633-638
  • Hacettepe University Affiliated: Yes

Abstract

Aim: To analyze the methylation status of the promoter regions of p16 and p27 genes in Wilms tumor patients. These tumor suppressor genes are associated with 2 main pathways regulating the G1/S transition of the cell cycle.