P16 and p27 tumor suppressor gene methylation status in childhood Wilms tumor cases

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Bozkurt C., BOZKURT S., Arda N., Ertem A. U., Sahin G., Yuksek N., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.41, sa.4, ss.633-638, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3906/sag-0909-296
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.633-638
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Aim: To analyze the methylation status of the promoter regions of p16 and p27 genes in Wilms tumor patients. These tumor suppressor genes are associated with 2 main pathways regulating the G1/S transition of the cell cycle.