Can serum matrix metalloproteinase-9 and SMAD-2 levels predict lamina propria invasion in bladder urothelial carcinoma?


Yitgin Y., ERDEM S., SERİLMEZ M., Duranyildiz D., Verep S., Gasimov K., ...More

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2021
  • Doi Number: 10.1111/ijcp.14277
  • Title of Journal : INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Abstract

Introduction Matrix metalloproteinase-9 (MMP-9) has a role in the destruction of lamina propria (LP) of the bladder wall and SMAD-2 promotes cell-to-cell adhesion. This study aimed to investigate the association between LP invasion and serum protein and mRNA expression levels of MMP-9 and SMAD-2 in bladder cancer (BC) patients.