Antioxidant flavonoids from Verbascum salviifolium boiss


AKDEMİR Z. Ş., Tatli İ. İ., Bedir E., Khan I. A.

Fabad Journal of Pharmaceutical Sciences, vol.28, no.2, pp.71-75, 2004 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 2
  • Publication Date: 2004
  • Journal Name: Fabad Journal of Pharmaceutical Sciences
  • Journal Indexes: Scopus
  • Page Numbers: pp.71-75
  • Hacettepe University Affiliated: Yes

Abstract

Phenolic natural products such as flavonoids are known as potential antioxidant compounds. The aim of this study was the isolation, structure elucidation and determination of radical scavenging properties of flavonoids which were guided by DPPH autographic assay from the methanolic extract of the aerial parts of Verbascum salviifolium. From the titled plant, four flavonoid glucosides, apigenin-7-O-β-glucopyranoside (1), luteolin-7-O-β- glucopyranoside (2), luteolin-3′-O-β-glucopyranoside (3), and chrysoeriol-7-O-β-glucopyranoside (4), were isolated. The structures of the compounds were established on the basis of the spectroscopic evidence. Compounds 1-4 demonstrated scavenging properties toward the 1,1-diphenyl-2- picrylhydrazyl (DPPH) radical in TLC autographic assays.