Hemophagocytic lymphohistiocytosis secondary to Varicella zoster infection in a child with Henoch-Schonlein purpura

Gur, Gokce; Cakar, Nilgun; Uncu, Nermin; Ayar, Ganime; Basaran, HALİDE; Taktak, Aysel; Koksoy, Adem; Acar, Banu; Cayci, Fatma

doi:10.1111/ped.12523

Hemophagocytic lymphohistiocytosis secondary to Varicella zoster infection in a child with Henoch-Schonlein purpura

Gur G., Cakar N., Uncu N., Ayar G., Basaran O., Taktak A., ...Daha Fazla

PEDIATRICS INTERNATIONAL, cilt.57, sa.2, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 57 Sayı: 2
Basım Tarihi: 2015
Doi Numarası: 10.1111/ped.12523
Dergi Adı: PEDIATRICS INTERNATIONAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe Üniversitesi Adresli: Evet

Özet

Hemophagocytic lymphohistiocytosis (HLH) is a fatal, hyper-inflammatory syndrome that is characterized by untimely activation of macrophages, and manifests as cytopenia, organ dysfunction, and coagulopathy. Secondary HLH can be associated with infection, drugs, malignancy, and transplantation, and is mostly triggered by infection. Herein, we report the case of a patient with Henoch-Schonlein purpura (HSP) who developed severe HLH secondary to Varicella zoster infection.