Hemophagocytic lymphohistiocytosis secondary to Varicella zoster infection in a child with Henoch-Schonlein purpura

Gur G., Cakar N., Uncu N., Ayar G., Basaran O. , Taktak A., ...Daha Fazla

PEDIATRICS INTERNATIONAL, cilt.57, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 57 Konu: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/ped.12523


Hemophagocytic lymphohistiocytosis (HLH) is a fatal, hyper-inflammatory syndrome that is characterized by untimely activation of macrophages, and manifests as cytopenia, organ dysfunction, and coagulopathy. Secondary HLH can be associated with infection, drugs, malignancy, and transplantation, and is mostly triggered by infection. Herein, we report the case of a patient with Henoch-Schonlein purpura (HSP) who developed severe HLH secondary to Varicella zoster infection.