Simple, Fast and Reliable Liquid Chromatographic and Spectrophotometric Methods for the Determination of Theophylline in Urine, Saliva and Plasma Samples

Charehsaz M., GÜRBAY A., Aydin A., Sahin G.

IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, vol.13, no.2, pp.431-439, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 2
  • Publication Date: 2014
  • Journal Name: IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.431-439
  • Keywords: Theophylline, Plasma, Saliva, Urine, HPLC, UV spectrophotometry, MAJOR METABOLITES, MICROSCALE PROCEDURE, BLOOD-SERUM, CAFFEINE, COLUMN, ASSAY
  • Hacettepe University Affiliated: Yes

Abstract

In this study, a high-performance liquid chromatographic method (HPLC) and UV spectrophotometric method were developed, validated and applied for the determination of theophylline in biological fluids.