Vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGFR-3 and D2-40 expressions in primary breast cancer: Association with lymph node metastasis
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.26, no.2, pp.245-249, 2017 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 26 Issue: 2
- Publication Date: 2017
- Doi Number: 10.17219/acem/58784
- Journal Name: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.245-249
- Keywords: breast cancer, metastasis, VEGF, D2-40, FACTOR-C, LYMPHANGIOGENESIS, CARCINOMA, ANGIOGENESIS, PROGNOSIS, DENSITY
- Open Archive Collection: AVESIS Open Access Collection
- Hacettepe University Affiliated: Yes
Abstract
Background. Two members of the vascular endothelial growth factor (VEGF) family, VEGF-C and -D, are known as lymphangiogenic growth factors and play an important role in tumor lymphangiogenesis via activation of the VEGF receptor (VEGFR)-3, which is expressed in lymphatic endothelial cells. D2-40 is a specific antibody for lymphatic vessel density (LVD).