Mutation analysis of the PARKIN, PINK1, DJ1, and SNCA genes in Turkish early-onset Parkinson's patients and genotype-phenotype correlations


Erer S., EGELİ Ü., ZARİFOĞLU M., Tezcan G., ÇEÇENER G., TUNCA B., ...More

CLINICAL NEUROLOGY AND NEUROSURGERY, vol.148, pp.147-153, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 148
  • Publication Date: 2016
  • Doi Number: 10.1016/j.clineuro.2016.07.005
  • Title of Journal : CLINICAL NEUROLOGY AND NEUROSURGERY
  • Page Numbers: pp.147-153

Abstract

Objective: Variations in PARK genes (PRKN, PINK1, DJ-1, and SNCA) cause early-onset Parkinson's disease (EOPD) in different populations. In the current study, we aimed to evaluate the frequencies of variations in PARK genes and the effects of these variations on the phenotypes of Turkish EOPD patients.