Features of Childhood Colorectal Carcinomas and Frequency of K-ras Mutations


BÜYÜKCAM A. , AKYÜZ C. , ORHAN D. , YALÇIN B. , VARAN A. , BÜYÜKPAMUKÇU M. , ...Daha Fazla

EUROPEAN JOURNAL OF THERAPEUTICS, cilt.27, sa.1, ss.20-25, 2021 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Konu: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/eurjther.2021.20034
  • Dergi Adı: EUROPEAN JOURNAL OF THERAPEUTICS
  • Sayfa Sayıları: ss.20-25

Özet

Objective: Colorectal carcinoma (CRC) is extremely rare in childhood and has a poor prognosis in young patients. The tumorigenesis of CRC in children and adolescents is still unclear and probably evolves through different stages. There are not enough studies about the rarity of K-ras mutations with childhood CRC. This study aimed to investigate the features and outcomes of childhood CRC as well as examine the frequency of K-ras mutations in CRC among children and adolescents.