Stobadine protects rat kidney against ischaemia/reperfusion injury

Guz G., Demirogullari B., Ulusu N. N., Dogu C., Demirtola A., Kavutcu M., ...More

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.34, no.3, pp.210-216, 2007 (SCI-Expanded) identifier identifier identifier


1. Ischaemia-reperfusion (I/R) injury, one of the main causes of acute renal failure, still needs satisfactory treatment for routine clinical application. Stobadine, a novel synthetic pyridoindole anti-oxidant, has the ability to reduce tissue injury induced by mechanisms involving reactive oxygen species during I/R. The aim of the present study was to determine the effects of stobadine on renal I/R injury.