Stobadine protects rat kidney against ischaemia/reperfusion injury

Guz, Galip; Demirogullari, Billur; Ulusu, Nuray; Dogu, Cihangir; Demirtola, Arzu; Kavutcu, Mustafa; Omeroglu, Suna; Stefek, Milan; Karasu, Cimen

doi:10.1111/j.1440-1681.2007.04574.x

Stobadine protects rat kidney against ischaemia/reperfusion injury

Guz G., Demirogullari B., Ulusu N. N., Dogu C., Demirtola A., Kavutcu M., ...Daha Fazla

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, cilt.34, sa.3, ss.210-216, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 34 Sayı: 3
Basım Tarihi: 2007
Doi Numarası: 10.1111/j.1440-1681.2007.04574.x
Dergi Adı: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.210-216
Hacettepe Üniversitesi Adresli: Hayır

Özet

1. Ischaemia-reperfusion (I/R) injury, one of the main causes of acute renal failure, still needs satisfactory treatment for routine clinical application. Stobadine, a novel synthetic pyridoindole anti-oxidant, has the ability to reduce tissue injury induced by mechanisms involving reactive oxygen species during I/R. The aim of the present study was to determine the effects of stobadine on renal I/R injury.