Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide

Pannek, S; Higgins, PG; Steinke, P; Jonas, D; Akova, M; Bohnert, JA; Seifert, H; Kern, WV

doi:10.1093/jac/dkl081

Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide

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Pannek S., Higgins P., Steinke P., Jonas D., Akova M., Bohnert J., ...More

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, vol.57, no.5, pp.970-974, 2006 (SCI-Expanded)

Publication Type: Article / Article
Volume: 57 Issue: 5
Publication Date: 2006
Doi Number: 10.1093/jac/dkl081
Journal Name: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.970-974
Hacettepe University Affiliated: No

Abstract

Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND-type efflux pumps but there are no data on its activity in non-fermenters like Acinetobacter.