Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide


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Pannek S., Higgins P., Steinke P., Jonas D., Akova M., Bohnert J., ...More

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, vol.57, no.5, pp.970-974, 2006 (SCI-Expanded, Scopus)

Abstract

Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND-type efflux pumps but there are no data on its activity in non-fermenters like Acinetobacter.