Poly(vinylferrocenium) coated disposable pencil graphite electrode for DNA hybridization

KURALAY F., ERDEM GÜRSAN K. A., ABACI S., Ozyoruk H., Yildiz A.

ELECTROCHEMISTRY COMMUNICATIONS, vol.11, no.6, pp.1242-1246, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 6
  • Publication Date: 2009
  • Doi Number: 10.1016/j.elecom.2009.04.010
  • Journal Name: ELECTROCHEMISTRY COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1242-1246
  • Hacettepe University Affiliated: Yes

Abstract

Poly(vinylferrocenium) (PVF+) modified electrode was developed in this study for the electrochemical sensing of DNA based on the oxidation signals of polymer, adenine and guanine. Experimental parameters, such as; polymeric film thickness, DNA immobilization time and DNA concentration were examined in order to obtain more sensitive and selective electrochemical signals. After optimization studies, DNA hybridization was investigated. (C) 2009 Elsevier B.V. All rights reserved.