A case of lupus vulgaris successfully treated with antituberculous therapy despite negative PCR and culture


Akoglu G., Karaduman A., Boztepe G., Ozkaya Ö., Sahin S., Erkin G., ...Daha Fazla

DERMATOLOGY, cilt.211, sa.3, ss.290-292, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 211 Sayı: 3
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1159/000087027
  • Dergi Adı: DERMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.290-292
  • Hacettepe Üniversitesi Adresli: Evet

Özet

A 14-year-old boy presented with a pink firm plaque with well-defined borders in the right infra-orbital skin area. On diascopy, the infiltrate exhibited a typical apple-jelly appearance. No acid-fast bacilli could be demonstrated. A polymerase chain reaction (PCR) assay did not reveal the presence of mycobacteria in a lesional biopsy sample. Culture of biopsied tissue on Loewenstein-Jensen medium was negative. Although the tuberculosis culture and PCR did not confirm tuberculosis, a diagnosis of lupus vulgaris was made considering the clinical and histopathological findings. After a 9-month antituberculous therapy, the lesion disappeared. We believe that a diagnosis of lupus vulgaris still depends more on clinical and histopathological findings than on tuberculosis culture or PCR.