A case of lupus vulgaris successfully treated with antituberculous therapy despite negative PCR and culture


Akoglu G., Karaduman A., Boztepe G., Ozkaya Ö. , Sahin S., Erkin G., ...Daha Fazla

DERMATOLOGY, cilt.211, ss.290-292, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 211 Konu: 3
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1159/000087027
  • Dergi Adı: DERMATOLOGY
  • Sayfa Sayıları: ss.290-292

Özet

A 14-year-old boy presented with a pink firm plaque with well-defined borders in the right infra-orbital skin area. On diascopy, the infiltrate exhibited a typical apple-jelly appearance. No acid-fast bacilli could be demonstrated. A polymerase chain reaction (PCR) assay did not reveal the presence of mycobacteria in a lesional biopsy sample. Culture of biopsied tissue on Loewenstein-Jensen medium was negative. Although the tuberculosis culture and PCR did not confirm tuberculosis, a diagnosis of lupus vulgaris was made considering the clinical and histopathological findings. After a 9-month antituberculous therapy, the lesion disappeared. We believe that a diagnosis of lupus vulgaris still depends more on clinical and histopathological findings than on tuberculosis culture or PCR.