Comparison of Myeloablative Versus Reduced-Intensity Conditioning Regimens for Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia: A Cohort Study

Ciftciler, Rafiye; GÖKER, HAKAN; DEMİROĞLU, HALUK; ALADAĞ KARAKULAK, ELİFCAN; AKSU, SALİH; HAZNEDAROĞLU, İBRAHİM; SAYINALP, NİLGÜN; Ozcebe, Osman; Tekin, Fatma; BÜYÜKAŞIK, YAHYA

doi:10.4274/tjh.galenos.2019.2018.0220

Comparison of Myeloablative Versus Reduced-Intensity Conditioning Regimens for Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia: A Cohort Study

Ciftciler R., GÖKER H., DEMİROĞLU H., ALADAĞ KARAKULAK E., AKSU S., HAZNEDAROĞLU İ. C., ...More

TURKISH JOURNAL OF HEMATOLOGY, vol.36, no.2, pp.88-96, 2019 (SCI-Expanded, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 36 Issue: 2
Publication Date: 2019
Doi Number: 10.4274/tjh.galenos.2019.2018.0220
Journal Name: TURKISH JOURNAL OF HEMATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.88-96
Open Archive Collection: AVESIS Open Access Collection
Hacettepe University Affiliated: Yes

Abstract

Objective: Allogeneic hematopoietic stem cell transplantation (HSCT) is an effective treatment modality for a variety of malignant and non-malignant hematologic disorders. Myeloablative conditioning (MAC) and reduced-intensity conditioning (RIC) regimens could have different clinical outcomes. This purpose of this study was to assess the long-term outcome of MAC versus RIC regimens in patients with acute myeloid leukemia (AML) undergoing allogeneic HSCT.