Recipient-derived hepatocytes in sex-mismatched liver allografts after liver transplantation: Early versus late transplant biopsies

Idilman R., Erden E., Kuzu I., Ersoz S., Karasu A. Z., Karayalcin K., ...Daha Fazla

TRANSPLANTATION, cilt.78, sa.11, ss.1647-1652, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 11
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1097/01.tp.0000144055.78462.4f
  • Dergi Adı: TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1647-1652
  • Anahtar Kelimeler: stem cells, liver transplantation, repopulation, hepatocyte, BONE-MARROW, CELLS, MICROCHIMERISM, FUSION
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Background. The presence of microchimerism in transplanted tissues is well defined; however, the timeframe of appearance and disappearance of engraftment in liver allograft is unknown. The aims of this study were to analyze for the presence of "recipient-derived cells" in sex-mismatched individuals after liver transplantation, comparing the frequency of "recipient-derived cell repopulation" in early versus late transplant biopsies and to evaluate the relationship between "recipient-derived cell repopulation" and the severity of graft injury.