Heritability of dehydroepiandrosterone sulfate in women with polycystic ovary syndrome and their sisters

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Yildiz B. O., Goodarzi M. O., Guo X., Rotter J. I., Azziz R.

FERTILITY AND STERILITY, vol.86, no.6, pp.1688-1693, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 86 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.1016/j.fertnstert.2006.05.045
  • Journal Name: FERTILITY AND STERILITY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1688-1693
  • Keywords: polycystic ovary, adrenal, genetics, androgen excess, phenotype, sibling, ADRENAL ANDROGEN EXCESS, INSULIN-RESISTANCE, DEGREE RELATIVES, HEALTHY WOMEN, GENETIC-BASIS, PREVALENCE, HYPERANDROGENEMIA, SECRETION, DEHYDROISOANDROSTERONE, REPLACEMENT
  • Hacettepe University Affiliated: Yes

Abstract

Objective: To test the hypothesis that adrenal androgen (AA) secretion is an inherited trait in PCOS and that serum DHEAS concentrations, as a marker of AA secretion, will be correlated between women with PCOS and their sisters.