Comparison of the Ovary and Kidney as Sites for Islet Transplantation in Diabetic Rats

Karakose M., Pinarli F. A., Arslan M. S., Boyuk G., Boztok B., Albayrak A., ...More

TRANSPLANTATION PROCEEDINGS, vol.48, no.6, pp.2216-2220, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.1016/j.transproceed.2016.04.017
  • Journal Name: TRANSPLANTATION PROCEEDINGS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2216-2220
  • Hacettepe University Affiliated: Yes

Abstract

Background. Currently, the most commonly used site for clinical islet transplantation is the liver although it is far from being an ideal site. Low oxygen tension and the induction of an inflammatory response impair islet implantation and lead to significant early loss of islet. The present study aimed to investigate and compare the efficacy of islet transplantation to the ovary and kidney subcapsule in diabetic rats.