Evaluation of protective effects of the alpha lipoic acid after spinal cord injury: An animal study

Tas N., BAKAR B., Kasimcan M. O., GAZYAĞCI S., Ayva S. K., Kilinc K., ...More

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, vol.41, no.10, pp.1068-1074, 2010 (SCI-Expanded) identifier identifier identifier


Purpose: Many of the hypotheses have been suggested to explain the mechanism of the secondary effects of traumatic spinal cord injury (TSCI) as follows: ischaemia/reperfusion disability theory, free radicals theory, exitotoxicity theory, immunological destruction theory, apoptosis theory. Recently, free radicals, lipid peroxidation reactions and apoptosis theories have been much more accepted than others. In this study, possible protective effects of the alpha lipoic acid were evaluated in the traumatic spinal cord of rats.