Evolution of clinically isolated syndrome to pediatric-onset multiple sclerosis and a review of the literature


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SOLMAZ İ., Oncel I.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.52, no.4, pp.1281-1287, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 52 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.55730/1300-0144.5434
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1281-1287
  • Keywords: Pediatric, clinically isolated syndrome, multiple sclerosis, predictive, TERM-FOLLOW-UP, PROGNOSTIC-FACTORS, INTERFERON BETA-1A, OLIGOCLONAL BANDS, CHILDREN, FEATURES, CHILDHOOD, CRITERIA, DEMYELINATION, DISABILITY
  • Hacettepe University Affiliated: Yes

Abstract

Background/aim: Clinically isolated syndrome (CIS) may be the first presentation of pediatric onset multiple sclerosis (POMS). We retrospectively evaluated the clinical and laboratory data of pediatric CIS (pCIS) patients who were diagnosed with POMS upon follow-up for any predictive variables. We also reviewed the literature concerning the management of pCIS.