Prognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study

Creative Commons License

Lacin S., YALÇIN Ş., Karakas Y., Hassan M. M., Amin H., Mohamed Y. I., ...More

JOURNAL OF HEPATOCELLULAR CARCINOMA, vol.7, pp.143-153, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7
  • Publication Date: 2020
  • Doi Number: 10.2147/jhc.s258930
  • Journal Name: JOURNAL OF HEPATOCELLULAR CARCINOMA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.143-153
  • Hacettepe University Affiliated: Yes

Abstract

Background: The Child-Turcotte-Pugh score (CTP) is the most commonly used tool to assess hepatic reserve and predict survival in hepatocellular cancer (HCC). The CTP stratification accuracy has been questioned and attempts have been made to improve the objectivity of the system. Serum insulin-like growth factor-1 (IGF-1)-CTP has been proposed to improve CTP prognostic accuracy. We aimed to validate the IGF-CTP score in our patient population.