Prognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study

Lacin, ŞAHİN; YALÇIN, ŞUAYİB; Karakas, Yusuf; Hassan, Manal; Amin, Hesham; Mohamed, Yehia; Rashid, Asif; Morris, Jeffrey; Xiao, Lianchun; Qayyum, Aliya; Kaseb, Ahmed

doi:10.2147/jhc.s258930

Prognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study

Lacin S., YALÇIN Ş., Karakas Y., Hassan M. M., Amin H., Mohamed Y. I., ...Daha Fazla

JOURNAL OF HEPATOCELLULAR CARCINOMA, cilt.7, ss.143-153, 2020 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7
Basım Tarihi: 2020
Doi Numarası: 10.2147/jhc.s258930
Dergi Adı: JOURNAL OF HEPATOCELLULAR CARCINOMA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
Sayfa Sayıları: ss.143-153
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: The Child-Turcotte-Pugh score (CTP) is the most commonly used tool to assess hepatic reserve and predict survival in hepatocellular cancer (HCC). The CTP stratification accuracy has been questioned and attempts have been made to improve the objectivity of the system. Serum insulin-like growth factor-1 (IGF-1)-CTP has been proposed to improve CTP prognostic accuracy. We aimed to validate the IGF-CTP score in our patient population.