IL-8 contributes to functional diversity of tumor-infiltrating neutrophils: A new target for cancer immunotherapy
DEVELOPMENTAL CELL, cilt.60, sa.3, ss.339-341, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 60 Sayı: 3
- Basım Tarihi: 2025
- Doi Numarası: 10.1016/j.devcel.2025.01.003
- Dergi Adı: DEVELOPMENTAL CELL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE, Nature Index
- Sayfa Sayıları: ss.339-341
- Hacettepe Üniversitesi Adresli: Evet
Özet
In this issue of Developmental Cell, Tang et al. identify CD74high neutrophils as a subpopulation promoted by IL-8 in the tumor microenvironment of non-small lung cancer (NSCLC). These CD74high neutrophils support anti-tumor T cell responses and enhance the efficacy of anti-PD-1 immunotherapy and targeted therapy in NSCLC.