Effect of maternal N-G-nitro-L-arginine administration on fetal growth and hypoxia-induced changes in newborn rats

Kilic I., Guven C., Kilinc K.

PEDIATRICS INTERNATIONAL, vol.45, no.4, pp.375-378, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1046/j.1442-200x.2003.01740.x
  • Journal Name: PEDIATRICS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.375-378
  • Hacettepe University Affiliated: No

Abstract

Background : Nitric oxide (NO) inhibition with N (G) -nitro-l-arginine methyl ester (l-NAME) in the last trimester of pregnancy caused intrauterine growth retardation and hind-limb disruptions in rats. In the present study, the effect of maternal NO inhibition with N (G) -nitro-l-arginine (l-NNA) on hypoxic newborn rats was investigated.