Effect of maternal N-G-nitro-L-arginine administration on fetal growth and hypoxia-induced changes in newborn rats


Kilic I., Guven C., Kilinc K.

PEDIATRICS INTERNATIONAL, cilt.45, ss.375-378, 2003 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 45 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1046/j.1442-200x.2003.01740.x
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Sayfa Sayıları: ss.375-378

Özet

Background : Nitric oxide (NO) inhibition with N (G) -nitro-l-arginine methyl ester (l-NAME) in the last trimester of pregnancy caused intrauterine growth retardation and hind-limb disruptions in rats. In the present study, the effect of maternal NO inhibition with N (G) -nitro-l-arginine (l-NNA) on hypoxic newborn rats was investigated.