Neopterin profile to evaluate the effectiveness of treatment in aggressive periodontitis

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Bodur A., Baydar T., Ozmeric N., Engin A., Uraz A., Eren K., ...More

PTERIDINES, vol.14, no.3, pp.77-81, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 3
  • Publication Date: 2003
  • Doi Number: 10.1515/pteridines.2003.14.3.77
  • Journal Name: PTERIDINES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77-81
  • Keywords: neopterin, gingival crevicular fluid, saliva, urine, aggressive periodontitis, GINGIVAL CREVICULAR FLUID, IMMUNE ACTIVATION, MARKER, SALIVA, URINE
  • Hacettepe University Affiliated: Yes


Periodontal disease results from the interaction of the host defence mechanisms with the microbial dental plaque. Analysis of gingival crevicular fluid (GCF) provides a non-invasive means of evaluating the role of the host response in periodontal disease. Based on our previous study, demonstrating increased levels of neopterin in GCF and saliva from patients with aggressive periodontitis (AgP), the aim of this study was to evaluate the effect of periodontal treatment on the levels of neopterin in GCF, saliva and urine of patients with AgP.