Role of gender and anatomical region on induction of osteogenic differentiation of human adipose-derived stem cells

Aksu A. E., Rubin J. P., Dudas J. R., Marra K. G.

ANNALS OF PLASTIC SURGERY, vol.60, no.3, pp.306-322, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 3
  • Publication Date: 2008
  • Doi Number: 10.1097/sap.0b013e3180621ff0
  • Journal Name: ANNALS OF PLASTIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.306-322
  • Hacettepe University Affiliated: No

Abstract

Adipose-derived stem cells (ASCs) display multilineage plasticity and, under appropriate conditions, can mineralize their extracellular matrix and undergo osteogenesis. The aims of this study are to examine in vitro osteogenic differentiation properties of ASCs to assess the role of gender, fat depot, and optimal duration as variables for differentiation.